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Introduction. Glucosamine hydrochloride and chondroitin sulfate are commonly used in dogs with OA, but evidence around efficacy is mixed. This study evaluated the effectiveness of glucosamine and chondroitin sulfate, marine based fatty acid compounds (PCSO-524 and EAB-277), and carprofen for the alleviation of canine hip OA pain.


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Glucosamine for dogs is commonly given to: Alleviate arthritis caused by joint instability (e.g. following ligament damage), trauma (e.g. fractures), damage to cartilage or abnormal development. Aid in the treatment of spinal disc injury. (link is external) . Ease recovery following joint surgery. Try to keep performance dogs. (link is external)


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Glucosamine and chondroitin are two of the most common supplements given to dogs with general joint problems and arthritis. Glucosamine and chondroitin are often paired together in a single supplement, as they work together to help with joint pain and flexibility.. Glucosamine is an amino sugar produced by the body that helps build cartilage.


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Despite limited and conflicting evidence, the natural products glucosamine hydrochloride (HCl) and chondroitin sulfate are commonly recommended by veterinarians for treating osteoarthritis in dogs. There is a paucity of well-designed clinical veterinary studies investigating the true treatment effect of glucosamine and chondroitin.


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After about 4-6 weeks, if a positive response is seen, the dose can be decreased in half (to the doses provided above) or given every other day. Fortunately, glucosamine and chondroitin have a very large safety threshold, so some tweaking at the advisement of your veterinarian to see what works best, can be considered.


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Glucosamine and chondroitin can be safely used in addition to other medications and therapies as a part of the treatment approach for the crippling effects of arthritis in cats and dogs. Veterinarians agree that the management of arthritis in both cats and dogs is best served in a multimodal manner, meaning that a combination of pain medications, supplements, acupuncture or physical therapy.


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The authors also concluded that glucosamine and chondroitin therapy was non-inferior to carprofen therapy at day 70 in the treatment of osteoarthritis in dogs. The McCarthy et al. (2007) trial was multi-centered, randomized, double-blinded, and prospective which is an ideal study design.


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Glucosamine increases the concentration of proteoglycans (large protein molecules) in cartilage and the synovial membrane which produces the fluid lubricating the joints. Also, Glucosamine may support the repair of damaged cartilage by increasing collagen deposition, providing joint care for dogs and cats.


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"Glucosamine and chondroitin are commonly recommended by veterinarians as an alternative for treating osteoarthritis in canines unable to tolerate the adverse effects of NSAIDs, or as add-on.


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Despite limited and conflicting evidence, the natural products glucosamine hydrochloride (HCl) and chondroitin sulfate are commonly recommended by veterinarians for treating osteoarthritis in dogs. There is a paucity of well-designed clinical veterinary studies investigating the true treatment effect of glucosamine and chondroitin.


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The safe dosage for glucosamine and chondroitin in dogs depends on their weight. As a general guideline, a dog might receive 20mg of glucosamine per pound of body weight and about 15mg of chondroitin per pound. However, dosages can vary depending on the product and your dog's specific needs, so always follow the instructions on the product.


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A veterinary systematic review on the use of chondroitin-glucosamine was also inconclusive in dogs . Like these previous reviews, the results of the present meta-analysis led to the conclusion that chondroitin-glucosamine nutraceuticals should not be prescribed in canine or feline OA.


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Like glucosamine, there are a lot of joint-related benefits of chondroitin for dogs. While glucosamine focuses on pain relief, chondroitin has more anti-inflammatory properties. It also helps in blocking and reducing enzyme levels. Enzymes that are always present in the joint break down cartilage.


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Glucosamine and chondroitin are frequently recommended health supplements that can help to support joint health and mobility in dogs. This is because glucosamine helps to regulate the synthesis of collagen in cartilage, while chondroitin can help limit the impact of destructive enzymes in cartilage and joint fluid.


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Glucosamine in dogs has mild side effects, if any at all, because it's a naturally occurring substance in the body. Possible side effects might include: Increased thirst. Increased urination. Trouble sleeping. Occasional vomiting or diarrhea. These side effects are brief and should go away after several doses.


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Medium dogs that weigh between 20 to 45 pounds should get 500 mg a day. Small dogs that weigh between 5 to 20 pounds a day should get 250 to 500 mg per day. There are also several different delivery methods available for glucosamine. The joint supplement can come as a pill, injection, powder, liquid, capsule or chewable tablet.